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CD55 Protein (AA 35-353) (His tag)

CD55 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN5855076
  • Target See all CD55 Proteins
    CD55 (Complement Decay-Accelerating Factor (CD55))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 35-353
    Origin
    • 8
    • 4
    • 2
    • 1
    • 1
    Human
    Source
    • 9
    • 4
    • 2
    • 1
    Baculovirus infected Insect Cells
    Purification tag / Conjugate
    This CD55 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    ADPDCGLPPD VPNAQPALEG RTSFPEDTVI TYKCEESFVK IPGEKDSVIC LKGSQWSDIE EFCNRSCEVP TRLNSASLKQ PYITQNYFPV GTVVEYECRP GYRREPSLSP KLTCLQNLKW STAVEFCKKK SCPNPGEIRN GQIDVPGGIL FGATISFSCN TGYKLFGSTS SFCLISGSSV QWSDPLPECR EIYCPAPPQI DNGIIQGERD HYGYRQSVTY ACNKGFTMIG EHSIYCTVNN DEGEWSGPPP ECRGKSLTSK VPPTVQKPTT VNVPTTEVSP TSQKTTTKTT TPNAQATRST PVSRTTKHFH ETTPNKGSGT TSHHHHHH
    Purity
    > 95 % by SDS - PAGE
    Endotoxin Level
    < 1.0 EU per 1ug of protein (determined by LAL method)
    Top Product
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  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target
    CD55 (Complement Decay-Accelerating Factor (CD55))
    Alternative Name
    CD55 (CD55 Products)
    Synonyms
    CR Protein, CROM Protein, DAF Protein, TC Protein, Daf Protein, Daf-GPI Protein, Daf1 Protein, GPI-DAF Protein, CD55 molecule (Cromer blood group) Protein, CD55 molecule, decay accelerating factor for complement Protein, CD55 Protein, Cd55 Protein
    Background
    CD55, also known as complement decay-accelerating factor isoform 1, is a membrane protein that attaches to cell membrane via a glycophosphatidylinositol (GPI) anchor. It contains four complement control protein repeats (CCPs) with a single N-linked glycan positioned between CCPs 1 and 2. It regulates the complement system on the cell surface. It is used as a receptor by some coxsackieviruses and other enteroviruses. It is broadly distributed among hematopoietic and non-hematopoietic cells. It is a determinant for the Cromer blood group system. It plays a role promotion of tumorigenesis, decrease of complement mediated tumor cell lysis, autocrine loops for cell rescue and evasion of apoptosis, neoangiogenesis, invasiveness, cell motility. Recombinant human CD55, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
    Molecular Weight
    36kDa (328aa) 40-57kDa (SDS-PAGE under reducing conditions)
    NCBI Accession
    NP_000565
    UniProt
    P08174
    Pathways
    Complement System, Regulation of Leukocyte Mediated Immunity
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