Hemopexin Protein (HPX) (AA 24-462) (His tag)
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- Target See all Hemopexin (HPX) Proteins
- Hemopexin (HPX)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 24-462
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This Hemopexin protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- ADPTPLPPTS AHGNVAEGET KPDPDVTERC SDGWSFDATT LDDNGTMLFF KGEFVWKSHK WDRELISERW KNFPSPVDAA FRQGHNSVFL IKGDKVWVYP PEKKEKGYPK LLQDEFPGIP SPLDAAVECH RGECQAEGVL FFQGDREWFW DLATGTMKER SWPAVGNCSS ALRWLGRYYC FQGNQFLRFD PVRGEVPPRY PRDVRDYFMP CPGRGHGHRN GTGHGNSTHH GPEYMRCSPH LVLSALTSDN HGATYAFSGT HYWRLDTSRD GWHSWPIAHQ WPQGPSAVDA AFSWEEKLYL VQGTQVYVFL TKGGYTLVSG YPKRLEKEVG TPHGIILDSV DAAFICPGSS RLHIMAGRRL WWLDLKSGAQ ATWTELPWPH EKVDGALCME KSLGPNSCSA NGPGLYLIHG PNLYCYSDVE KLNAAKALPQ PQNVTSLLGC THHHHHHH
- Purity
- > 90% by SDS-PAGE
- Endotoxin Level
- < 1 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product HPX Protein
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Hemopexin (HPX) (AA 24-462) protein (His tag)
HPX Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Hemopexin (HPX) (AA 24-460) protein (His tag)HPX Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Hemopexin (HPX) (AA 24-462) protein (His tag)HPX Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Hemopexin (HPX) (AA 24-460) protein (His tag)HPX Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Hemopexin (HPX) (AA 1-254) protein (GST tag)HPX Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Hemopexin (HPX) (Active) protein (His tag)HPX Origin: Mouse Host: HEK-293 Cells Recombinant > 98 % as determined by SDS-PAGE Active
Hemopexin (HPX) proteinHPX Origin: Human Host: Human Native >95 %
Hemopexin (HPX) (AA 24-460), (full length) protein (His tag)HPX Origin: Rat Host: Yeast Recombinant > 90 % ELISA
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- Target
- Hemopexin (HPX)
- Alternative Name
- Hemopexin (HPX Products)
- Background
- HPX, also known as hemopexin, is a plasma glycoprotein that belongs to the family of the acute-phase proteins whose synthesis is induced after an inflammatory event. This protein associates with HDL and influence the inflammatory properties of HDL. In addition it can also be said that HDL from HX-null mice is pro-inflammatory. Also, this protein binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation and is expressed in the central nervous system, in the retina, and in peripheral nerves has also been observed. Recombinant human HPX, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 50.4 kDa (448aa)
- NCBI Accession
- NP_000604
- UniProt
- P02790
- Pathways
- Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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