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Hemopexin Protein (HPX) (AA 24-462) (His tag)

HPX Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7274826
  • Target See all Hemopexin (HPX) Proteins
    Hemopexin (HPX)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 24-462
    Origin
    • 10
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Cynomolgus
    Source
    • 8
    • 6
    • 5
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Hemopexin protein is labelled with His tag.
    Purpose
    Cynomolgus HPX Protein
    Sequence
    Asn24-Tyr462
    Characteristics
    Recombinant Cynomolgus HPX Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asn24-Tyr462.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product HPX Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in 20 mM MES, 150 mM NaCl ( pH 6.0).
    Buffer
    Lyophilized from 0.22μm filtered solution in 20 mM MES, 150 mM NaCl ( pH 6.0). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    Hemopexin (HPX)
    Alternative Name
    HPX (HPX Products)
    Synonyms
    HPX Protein, HX Protein, Hpxn Protein, hx Protein, wu:fi17f11 Protein, wu:fi19a10 Protein, hemopexin Protein, HPX Protein, Mmar10_1124 Protein, Hpx Protein, hpx Protein
    Background
    Hemopexin (HPX) serves as scavenger and transporter of toxic plasma heme to the liver. HPX is formed by two four-bladed beta-propeller domains, resembling two thick disks that lock together at a 90 degrees angle. The heme is bound between the two beta-propeller domains in a pocket formed by the interdomain linker peptide.HPX, acting not only as a heme carrier but also displaying transient heme-based ligand binding and (pseudo-)enzymatic properties, could be considered a 'chronosteric' heme-protein.
    Molecular Weight
    50.30 kDa. Due to glycosylation, the protein migrates to 60-80 kDa based on Tris-Bis PAGE result.
    UniProt
    A0A2K5WVL1
    Pathways
    Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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