TNFRSF21 Protein (AA 42-349) (hIgG-His-tag)
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- Target See all TNFRSF21 Proteins
- TNFRSF21 (Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 42-349
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This TNFRSF21 protein is labelled with hIgG-His-tag.
- Application
- SDS-PAGE (SDS)
- Sequence
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QPEQKASNLI GTYRHVDRAT GQVLTCDKCP AGTYVSEHCT NTSLRVCSSC PVGTFTRHEN GIEKCHDCSQ PCPWPMIEKL PCAALTDREC TCPPGMFQSN ATCAPHTVCP VGWGVRKKGT ETEDVRCKQC ARGTFSDVPS SVMKCKAYTD CLSQNLVVIK PGTKETDNVC GTLPSFSSST SPSPGTAIFP RPEHMETHEV PSSTYVPKGM NSTESNSSAS VRPKVLSSIQ EGTVPDNTSS ARGKEDVNKT LPNLQVVNHQ QGPHHRHILK LLPSMEATGG EKSSTPIKGP KRGHPRQNLH KHFDINEH
- Purity
- > 85% by SDS-PAGE
- Endotoxin Level
- < 1 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product TNFRSF21 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol, 0.1 mM PMSF.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- Target
- TNFRSF21 (Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21))
- Alternative Name
- DR6/TNFRSF21 (TNFRSF21 Products)
- Background
- TNFRSF21, also known as tumor necrosis factor receptor superfamily member 21, is a transmembrane protein in the TNF receptor superfamily. It promotes apoptosis through the activation of NF-kappa-B pathway. Binding of N-terminal APP (N-APP) and TNFRSF21 triggers caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6). This protein plays a role in signaling cascades triggered by stimulation of T-cell receptor. Recombinant human TNFRSF21 protein, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 60.4 kDa (547aa)
- NCBI Accession
- NP_055267
- UniProt
- O75509
- Pathways
- Regulation of Lipid Metabolism by PPARalpha
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