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Transferrin Protein (TF) (full length)

This Native Transferrin protein is expressed in .
Catalog No. ABIN7479567

Quick Overview for Transferrin Protein (TF) (full length) (ABIN7479567)

Target

See all Transferrin (TF) Proteins
Transferrin (TF)

Protein Type

Native

Origin

  • 15
  • 7
  • 6
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
Human

Host

Please inquire

Application

Western Blotting (WB), ELISA

Purity

> 90 %(SDS-PAGE)
  • Protein Characteristics

    full length

    Characteristics

    Full length native Human Transferrin

    Purification

    Purified from Human plasma
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    PBS
  • Target

    Transferrin (TF)

    Alternative Name

    Transferrin protein

    Background

    Background: Transferrin is a single polypeptide chain glycoprotein and is a member of the iron binding family of proteins. It has a molecular weight of 77 kDa and a serum concentration range of 1800 to 2700 mg/L. It is synthesized in the liver and consists of two domains each having a high affinity reversible binding site for Fe3+. Iron is transported in blood and interstitial fluids to sites of use and disposal. Iron/transferrin is essential in hemoglobin synthesis and for certain types of cell division. Serum concentration rises in iron deficiency and pregnancy and falls in iron overload, infection and inflammatory conditions. The function of transferrin is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. In addition to its function in iron transport, this protein may also have a physiologic role as granulocyte/pollen binding protein (GPBP) involved in the removal of certain organic matter/allergens from serum. Synonyms: Serotransferrin, Beta-1 metal-binding globulin, Siderophilin.

    Pathways

    Transition Metal Ion Homeostasis
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