SPA Protein

Catalog No. ABIN620966

This Recombinant SPA protein is expressed in .

Quick Overview for SPA Protein (ABIN620966)

Target: SPA (Immunoglobulin G Binding Protein A (SPA))

Protein Type: Recombinant

Origin: Staphylococcus aureus

Host: Please inquire

Purity: > 98.0 % as determined by RP-HPLC.

Product Details

Characteristics: Recombinant Staphylococcal Protein A

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The protein solution contains no additives.

Storage: -20 °C

Target Details

Target: SPA (Immunoglobulin G Binding Protein A (SPA))

Alternative Name: Staphylococcal Protein A

Background: Recombinant Staphylococcal Protein A produced in E.Coli is a non-glycosylated, Polypeptide chain having a molecular mass of 45 kDa. Recombinant Staphylococcal Protein A is purified by proprietary chromatographic techniques. Introduction: Protein A is a cell wall protein deriving from Staphylococcus aureus which exhibits unique binding properties for IgG from a variety of mammalian species and for some IgM and IgA as well. It binds with the Fc region of immunoglobulins through interaction with the heavy chain. It couples to a wide variety of reporter molecules including fluorescent dyes, enzyme markers, biotin, colloidal gold and radioactive iodine without affecting the antibody binding site. Recombinant Protein A was developed to increase the specificity of the molecule for IgG and is widely used both in research and bioprocessing. The recombinant protein A is produced by expressing a modified protein A gene in E.coli. A specific purification process with strict quality control was taken to get the recombinant protein A with the purity of more than 98% , no human IgG affinity step is used during validated fermentation and purification and devoid of bacterial contaminant found normally in native Protein A. (Free of Staphylococcus endotoxins and hemolysin). Synonyms: Immunoglobulin G-binding protein A, IgG-binding protein A, Staphylococcal protein A, SPA.