SPA Protein
SPA
Origin: Staphylococcus aureus
Recombinant
> 98.0 % as determined by RP-HPLC.
-
- Target See all SPA products
- SPA (Immunoglobulin G Binding Protein A (SPA))
- Protein Type
- Recombinant
-
Origin
- Staphylococcus aureus
- Host
- Please inquire
- Characteristics
- Recombinant Staphylococcal Protein A
- Purity
- > 98.0 % as determined by RP-HPLC.
-
-
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- The protein solution contains no additives.
- Storage
- -20 °C
-
- Target
- SPA (Immunoglobulin G Binding Protein A (SPA))
- Alternative Name
- Staphylococcal Protein A (SPA Products)
- Background
- Recombinant Staphylococcal Protein A produced in E.Coli is a non-glycosylated, Polypeptide chain having a molecular mass of 45 kDa. Recombinant Staphylococcal Protein A is purified by proprietary chromatographic techniques. Introduction: Protein A is a cell wall protein deriving from Staphylococcus aureus which exhibits unique binding properties for IgG from a variety of mammalian species and for some IgM and IgA as well. It binds with the Fc region of immunoglobulins through interaction with the heavy chain. It couples to a wide variety of reporter molecules including fluorescent dyes, enzyme markers, biotin, colloidal gold and radioactive iodine without affecting the antibody binding site. Recombinant Protein A was developed to increase the specificity of the molecule for IgG and is widely used both in research and bioprocessing. The recombinant protein A is produced by expressing a modified protein A gene in E.coli. A specific purification process with strict quality control was taken to get the recombinant protein A with the purity of more than 98% , no human IgG affinity step is used during validated fermentation and purification and devoid of bacterial contaminant found normally in native Protein A. (Free of Staphylococcus endotoxins and hemolysin). Synonyms: Immunoglobulin G-binding protein A, IgG-binding protein A, Staphylococcal protein A, SPA.
-
You are here:
