CMV Pp150 (AA 1011-1048) Protein
Quick Overview for CMV Pp150 (AA 1011-1048) Protein (ABIN621826)
Target
Protein Type
Origin
Host
Application
Purity
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Protein Characteristics
- AA 1011-1048
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Specificity
- Immunoreactive with sera of CMV-infected individuals.
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Characteristics
- Recombinant Cytomegalovirus pp150 (UL32)
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Purification
- CMV Pp150 was purified by proprietary chromatographic technique.
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Application Notes
- CMV Pp65 antigen is suitable for ELISA and Western blots, excellent antigen for detection of CMV with minimal specificity problems.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 25 mM Tris-Hcl pH 8.0, 5 mM EDTA and 50 % glycerol.
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Storage
- -20 °C
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- CMV Pp150
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Target Type
- Viral Protein
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Background
- The E.Coli derived recombinant protein contains the CMV Pp150 (UL32) immunodominant regions, 1011-1048 amino acids. Introduction: CMV belongs to the Betaherpesvirinae subfamily of Herpesviridae which includes herpes simplex virus types 1 and 2, varicella-zoster virus, and Epstein-Barrvirus. The herpes viruses share a characteristic ability to remain latent over long periods. CMV is a double-stranded linear DNA virus with 162 hexagonal protein capsomeres surrounded by a lipid membrane. CMV has the largest genome of the herpes viruses, ranging from 230-240 kilobase pairs. Human CMV is composed of unique and inverted repeats that include the existence of 4 genome isomers caused by inversion of L-S genome components (class E). Replication may be divided into immediate early, delayed early, and late gene expression based on time of synthesis after infection. The DNA is replicated by rolling circles. In vitro, CMV replicates in human fibroblasts.
Target
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