Complement C3b Protein

Catalog No. ABIN622147

Native Complement C3b protein expressed in Human.

Quick Overview for Complement C3b Protein (ABIN622147)

Target: Complement C3b (C3b) (Complement C3 beta Chain (C3b))

Protein Type: Native

Origin: Human

Source: Human

Purity: > 90 %. By SDS-PAGE

Product Details

Characteristics: Native Human C3b

Purification: Purified C3b from human serum

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/ml

Buffer: Phosphate buffered saline, pH 7.2

Storage: -20 °C

Target Details

Target: Complement C3b (C3b) (Complement C3 beta Chain (C3b))

Alternative Name: C3b

Background: Cleavage of the C3-alpha chain at peptide bond 77 results in production of C3a and C3b fragments. The C3b fragment is a glycoprotein composed of the modified C3-alpha chain and the intact C3-beta chain. Nascent C3b has the transient ability to form a covalent ester bond with a variety of target surfaces. Once bound to target surfaces C3b becomes an essential subunit of both the classical and alternative pathway C5 cleaving enzymes.

Molecular Weight: 180 kDa

Pathways: Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling