Galectin 3 Protein (LGALS3) (Soluble)
Quick Overview for Galectin 3 Protein (LGALS3) (Soluble) (ABIN624591)
Target
See all Galectin 3 (LGALS3) ProteinsProtein Type
Origin
Host
Purity
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Protein Characteristics
- Soluble
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Specificity
- Galectin-3 (Gal-3) is a member of the galectin family of beta-galactoside-binding proteins, which is involved in both intracellular and extracellular functions and exhibits anti-apoptotic properties. Gal-3 is implicated in many biological processes, including cell differentiation, growth, adhesion, angiogenesis and inflammation, and is expressed in a wide range of neoplasms. Gal-3 acts as a regulator of tumor metastasis, and several studies have shown a correlation between levels of Gal-3 and tumor progression in liver, thyroid, colon, gastric and breast carcinomas, making Gal-3 an emerging cancer marker. Activity: Determined by its ability to chemoattract human blood monocytes. Chemotactic activity was observed at a concentration of 2.5 µg/ml with a peak response obtained at 250 µg/ml.
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Characteristics
- Recombinant Human Galectin-3
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Purification
- Purified
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Endotoxin Level
- < 1 EU/ug
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute with 0.5 ml distilled water
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Concentration
- Total protein concentration 0.1 mg/ml after reconstitution
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Buffer
- Phosphate buffered saline
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Storage
- 4 °C
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- Galectin 3 (LGALS3)
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Alternative Name
- Galectin-3
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Target Type
- Chemical
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Background
- Synonyms: MAC2 Purified recombinant galectin-3 expressed in E.coli.
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Molecular Weight
- 26.0kD (250 amino acid residues)
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Pathways
- RTK Signaling
Target
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