IL-22 Protein (AA 34-179) (His tag)

Catalog No. ABIN7278736

This Recombinant IL-22 protein is expressed in Escherichia coli (E. coli).

Quick Overview for IL-22 Protein (AA 34-179) (His tag) (ABIN7278736)

Target: IL-22 (IL22) (Interleukin 22 (IL22))

Protein Type: Recombinant

Origin: Mouse

Source: Escherichia coli (E. coli)

Purity: >95 % (SDS-PAGE)

Product Details

Protein Characteristics: AA 34-179

Purification tag / Conjugate: This IL-22 protein is labelled with His tag.

Purpose: IL-22 (mouse) (rec.) (His)

Specificity: Mouse IL-22 (aa 34-179) is fused at the N-terminus to a His-tag.

Characteristics: Protein. Mouse IL-22 (aa 34-179) is fused at the N-terminus to a His-tag. Source: E. coli. Endotoxin content: <1EU/μg protein (LAL test, Lonza). Lyophilized from 0.2μm-filtered solution in PBS. Purity: >95 % (SDS-PAGE). Interleukin-22 (IL-22), also known as IL-10 related T cell-derived-inducible factor (ILTIF) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. IL-22 has been shown to activate STAT1 and STAT3 in several hepatoma cell lines and upregulate the production of acute phase proteins. IL-22 is produced by normal T cells upon anti-CD3 stimulation in humans. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. The functional IL-22 receptor complex consists of two receptor subunits, IL-22R(CRF29) and IL-10Rbeta(CRF24), belonging to the class II cytokine receptor family.

Endotoxin Level: <1EU/μg protein (LAL test, Lonza).

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized from 0.2μm-filtered solution in PBS.

Handling Advice: Avoid freeze/thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment:

Short Term Storage: +4°C

Long Term Storage: -20°C

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

Target Details

Target: IL-22 (IL22) (Interleukin 22 (IL22))

Alternative Name: IL-22

Background:

Alternate Names/Synonyms: Interleukin-22, IL-10-related T Cell-derived-inducible Factor, ILTIF

Product Description: Interleukin-22 (IL-22), also known as IL-10 related T cell-derived-inducible factor (ILTIF) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. IL-22 has been shown to activate STAT1 and STAT3 in several hepatoma cell lines and upregulate the production of acute phase proteins. IL-22 is produced by normal T cells upon anti-CD3 stimulation in humans. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. The functional IL-22 receptor complex consists of two receptor subunits, IL-22R(CRF29) and IL-10Rbeta(CRF24), belonging to the class II cytokine receptor family.

NCBI Accession: NP_058667