Liver Arginase Protein (active Mutant)
Quick Overview for Liver Arginase Protein (active Mutant) (ABIN6253489)
Target
See all Liver Arginase (ARG1) ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- active Mutant
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Purpose
- Arginase I (human) (rec.) (highly active)
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Specificity
- Full length human arginase I.
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Cross-Reactivity
- Human
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Characteristics
- Full length human arginase I.
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Biological Activity Comment
- 1.6 ±0.2U/μg protein. One unit is defined as the amount of enzyme that converts 1μmol of L-arginine to L-ornithine and urea per min. at 37°C, pH 9.5 (according to protocol from R.T. Schimke, et al., J. Biol. Chem. 238, 1012 (1963)).
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Arginase, Liver (ARG1) (AA 1-322) protein (His tag)
custom-made ARG1 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Arginase, Liver (ARG1) (AA 1-323) protein (His tag)custom-made ARG1 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Arginase, Liver (ARG1) (AA 1-322) protein (GST tag)ARG1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Arginase, Liver (ARG1) protein (MYC tag,His tag)ARG1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Arginase, Liver (ARG1) (Active) protein (Myc-DYKDDDDK Tag)ARG1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD Active
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.2 μg/μL
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Buffer
- In 10 mM TRIS-HCl, pH 7.5, containing 1 mM beta-mercaptoethanol, 1 mM MnCl2 and 50 % glycerol.
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Handling Advice
- Avoid freeze/thaw cycles.
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Storage
- -20 °C,-80 °C
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Storage Comment
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Short Term Storage: -20°C
Long Term Storage: -80°C
Use & Stability: Stable for at least 1 year after receipt when stored at -80°C.
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Expiry Date
- 12 months
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- Liver Arginase (ARG1) (Arginase, Liver (ARG1))
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Alternative Name
- Arginase I
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Background
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EC 3.5.3.1, ARG1, Arginase 1, Type I Arginase, Liver-type Arginase, L-Arginase
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Arginase is involved in the nitric oxide (NO) pathway and immune cell arginine metabolism. It is fundamentally involved in cancer, inflammation, infections, fibrotic diseases, neurobiology, pregnancy and immune regulation in general.
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Molecular Weight
- 34.7kDa
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UniProt
- P05089
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Pathways
- Cellular Response to Molecule of Bacterial Origin
Target
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