Liver Arginase Protein (AA 1-322) (His tag)
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- Target See all Liver Arginase (ARG1) Proteins
- Liver Arginase (ARG1) (Arginase, Liver (ARG1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-322
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Liver Arginase protein is labelled with His tag.
- Sequence
- Met1-Lys322
- Characteristics
- A DNA sequence encoding the human Arginase-1 (1M-322K) was expressed with a polyhistidine tag at the N-terminus.
- Purity
- >90 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product ARG1 Protein
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Arginase, Liver (ARG1) (AA 1-322) protein (GST tag)
ARG1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Arginase, Liver (ARG1) protein (His tag)ARG1 Origin: Human Host: Escherichia coli (E. coli) Recombinant >90 % as determined by reducing SDS-PAGE.
Arginase, Liver (ARG1) protein (MYC tag,His tag)ARG1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Arginase, Liver (ARG1) (AA 1-323) protein (Strep Tag)Crystallography grade ARG1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Arginase, Liver (ARG1) (Active) protein (Myc-DYKDDDDK Tag)ARG1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD Active
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as sterile solution of 25 mM Tris-HCl+150 mM KCl+1 mM DTT+20 % glycerol, pH 8.0.
- Preservative
- Dithiothreitol (DTT)
- Precaution of Use
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- Liver Arginase (ARG1) (Arginase, Liver (ARG1))
- Alternative Name
- Arginase-1 (ARG1 Products)
- Synonyms
- SI:zC146F4.4 (novel protein with NUDIX domain) Protein, si:ch211-146f4.3 Protein, argi1 Protein, AI Protein, AI256583 Protein, Arg-1 Protein, PGIF Protein, arginase 1 Protein, arginase Protein, Arginase-1 Protein, arginase, liver Protein, L-arginase Protein, arg1 Protein, PGTG_16455 Protein, argi1 Protein, ARG1 Protein, Arg1 Protein
- Background
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Background: Arginase 1, also known as liver arginase, is a binuclear manganese metalloenzyme. It is a key enzyme of the urea cycle that catalyses the conversion of L-arginine into L-ornithine and urea, the final cytosolic reaction of urea formation in the mammalian liver. Arginase 1 is abundantly expressed in liver, but it is also expressed in cells and tissues that lack a complete urea cycle, including lung. Arginase is a critical regulator of nitric oxide synthesis and vascular function. It is implicated in a variety of human diseases including vascular disease, pulmonary disease, infectious disease, immune cell function and cancer. In humans, hereditary defects in arginase result in an accumulation of arginine in the blood known as hyperarginemia. Arginase deficiency can also result in the accumulation of nitrogen in the form of ammonia, which results in hyperammonemia.
Synonym: ARG1,Al,Arginase 1,Arginase liver,
- Molecular Weight
- 36.9 kDa
- UniProt
- P05089
- Pathways
- Cellular Response to Molecule of Bacterial Origin
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