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Liver Arginase Protein (MYC tag,His tag)

ARG1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7317033
  • Target See all Liver Arginase (ARG1) Proteins
    Liver Arginase (ARG1) (Arginase, Liver (ARG1))
    Protein Type
    Recombinant
    Origin
    • 10
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Liver Arginase protein is labelled with MYC tag,His tag.
    Purpose
    Recombinant Human Arginase-1/ARG1 Protein (His & MYC Tag)
    Sequence
    Met 1-Lys 322
    Characteristics
    A DNA sequence encoding the human ARG1 (NP_000036.2) (Met1-Lys322) was expressed with a polyhistidine tag at the N-terminus and a myc tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product ARG1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 20 % glycerol, pH 7.4
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    Liver Arginase (ARG1) (Arginase, Liver (ARG1))
    Alternative Name
    Arginase-1 (ARG1 Products)
    Synonyms
    SI:zC146F4.4 (novel protein with NUDIX domain) Protein, si:ch211-146f4.3 Protein, argi1 Protein, AI Protein, AI256583 Protein, Arg-1 Protein, PGIF Protein, arginase 1 Protein, arginase Protein, Arginase-1 Protein, arginase, liver Protein, L-arginase Protein, arg1 Protein, PGTG_16455 Protein, argi1 Protein, ARG1 Protein, Arg1 Protein
    Background

    Background: Arginase is the focal enzyme of the urea cycle hydrolysing L-arginine to urea and L-ornithine. Emerging studies have identified arginase in the vasculature and have implicated this enzyme in the regulation of nitric oxide (NO) synthesis and the development of vascular disease. Arginase also redirects the metabolism of L-arginine to L-ornithine and the formation of polyamines and L-proline, which are essential for smooth muscle cell growth and collagen synthesis. Arginase is encoded by two recently discovered genes (Arginase I and Arginase II). In most mammals, Arginase 1 (ARG1) also known as Arginase, liver, which functions in the urea cycle, and is located primarily in the cytoplasm of the liver. The second isozyme, Arginase II, has been implicated in the regulation of the arginine/ornithine concentrations in the cell. It is located in mitochondria of several tissues in the body, with most abundance in the kidney and prostate. It may be found at lower levels in macrophages, lactating mammary glands, and brain.

    Synonym: Arginase-1, Liver-type arginase, Type I arginase, ARG1

    Molecular Weight
    36.7 kDa
    NCBI Accession
    NP_000036
    Pathways
    Cellular Response to Molecule of Bacterial Origin
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