LILRB3 Protein (AA 24-443) (Fc Tag)
Quick Overview for LILRB3 Protein (AA 24-443) (Fc Tag) (ABIN6253709)
Target
See all LILRB3 ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 24-443
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Purification tag / Conjugate
- This LILRB3 protein is labelled with Fc Tag.
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Sequence
- AA 24-443
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Characteristics
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 72.8 kDa. As a result of glycosylation, the protein migrates as 90-115 kDa under reducing (R) condition, and 150 kDa under non-reducing (NR) condition (SDS-PAGE
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Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
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Handling Advice
- Please avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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- LILRB3 (Leukocyte Immunoglobulin-Like Receptor B3 (LILRB3))
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Alternative Name
- LILRB3
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Background
- Leukocyte immunoglobulin-like receptor subfamily B member 3 is also known as LILRB3,ILT-5 or CD85a. LILRB3 plays an role as receptor for class I MHC antigens, which activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. LILRB3 and LILRA6 represent a pair of inhibitory/activating receptors with identical extracellular domains and unknown ligands. LILRB3 can mediate inhibitory signaling via immunoreceptor tyrosine-based inhibition motifs in its cytoplasmic tail whereas LILRA6 can signal through association with an activating adaptor molecule, FcRγ.
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Molecular Weight
- 72.8 kDa
Target
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