CRTAP Protein (AA 27-401) (His tag)
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- Target See all CRTAP Proteins
- CRTAP (Cartilage Associated Protein (CRTAP))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 27-401
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CRTAP protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSQYERYSF RSFPRDELMP LESAYRHALD KYSGEHWAES VGYLEISLRL HRLLRDSEAF CHRNCSAAPQ PEPAAGLASY PELRLFGGLL RRAHCLKRCK QGLPAFRQSQ PSREVLADFQ RREPYKFLQF AYFKANNLPK AIAAAHTFLL KHPDDEMMKR NMAYYKSLPG AEDYIKDLET KSYESLFIRA VRAYNGENWR TSITDMELAL PDFFKAFYEC LAACEGSREI KDFKDFYLSI ADHYVEVLEC KIQCEENLTP VIGGYPVEKF VATMYHYLQF AYYKLNDLKN AAPCAVSYLL FDQNDKVMQQ NLVYYQYHRD TWGLSDEHFQ PRPEAVQFFN VTTLQKELYD FAKENIMDDD EGEVVEYVDD LLELEETS
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product CRTAP Protein
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Cartilage Associated Protein (CRTAP) (AA 307-401) protein (GST tag)
CRTAP Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cartilage Associated Protein (CRTAP) (AA 27-401) protein (His tag)Crystallography grade CRTAP Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Cartilage Associated Protein (CRTAP) (AA 26-400) protein (His tag)Crystallography grade CRTAP Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Cartilage Associated Protein (CRTAP) protein (Myc-DYKDDDDK Tag)CRTAP Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M urea, 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- CRTAP (Cartilage Associated Protein (CRTAP))
- Alternative Name
- CRTAP (CRTAP Products)
- Synonyms
- zgc:85621 Protein, wu:fb47h01 Protein, CASP Protein, LEPREL3 Protein, OI7 Protein, 5730529N23Rik Protein, Leprel3 Protein, RGD1565180 Protein, cartilage associated protein Protein, cartilage-associated protein Protein, crtap Protein, CRTAP Protein, LOC5574430 Protein, CpipJ_CPIJ013810 Protein, Crtap Protein
- Background
- Cartilage-associated protein precursor, also known as CRTAP, is a secreted protein localizing to the extracellular space that plays a role in collagen post-translational modifications, extracellular fibril assembly and intracellular trafficking. CRTAP is widely expressed with predominant expression in articular chondrocytes. Mutations in the gene encoding CRTAP can lead to autosomal recessive osteogenesis imperfecta (OI) type 7 and type 2B. OI, also known as brittle bone disease, is characterized by bone fragility and susceptibility to fractures. Recombinant human CRTAP protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 46.4 kDa (398aa)
- NCBI Accession
- NP_006362
- UniProt
- O75718
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