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EXOSC3 Protein (AA 1-275) (His tag)

Recombinant EXOSC3 protein expressed in Escherichia coli (E. coli).
Catalog No. ABIN7280693

Quick Overview for EXOSC3 Protein (AA 1-275) (His tag) (ABIN7280693)

Target

See all EXOSC3 Proteins
EXOSC3 (Exosome Component 3 (EXOSC3))

Protein Type

Recombinant

Origin

  • 5
  • 1
  • 1
  • 1
Human

Source

  • 3
  • 2
  • 2
  • 1
Escherichia coli (E. coli)

Application

SDS-PAGE (SDS)

Purity

> 85 % by SDS - PAGE
  • Protein Characteristics

    AA 1-275

    Purification tag / Conjugate

    This EXOSC3 protein is labelled with His tag.

    Sequence

    MGSSHHHHHH SSGLVPRGSH MGSMAEPASV AAESLAGSRA RAARTVLGQV VLPGEELLLP EQEDAEGPGG AVERPLSLNA RACSRVRVVC GPGLRRCGDR LLVTKCGRLR HKEPGSGSGG GVYWVDSQQK RYVPVKGDHV IGIVTAKSGD IFKVDVGGSE PASLSYLSFE GATKRNRPNV QVGDLIYGQF VVANKDMEPE MVCIDSCGRA NGMGVIGQDG LLFKVTLGLI RKLLAPDCEI IQEVGKLYPL EIVFGMNGRI WVKAKTIQQT LILANILEAC EHMTSDQRKQ IFSRLAES
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  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.5 mg/mL

    Buffer

    Liquid. In 20  mM Tris-HCl buffer (  pH 7.5 containing 0.15M NaCl, 30 % glycerol, 1  mM DTT

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target

    EXOSC3 (Exosome Component 3 (EXOSC3))

    Alternative Name

    EXOSC3

    Background

    EXOSC3 is a non-catalytic component of the human exosome, a complex with 3'-5' exoribonuclease activity that plays a role in numerous RNA processing and degradation activities. Related pseudogenes of this gene are found on chromosome 19 and 21. Alternatively spliced transcript variants encoding different isoforms have been described. Recombinant human EXOSC3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

    Molecular Weight

    32.0 kDa (298aa) confirmed by MALDI-TOF

    NCBI Accession

    NP_057126

    UniProt

    Q9NQT5

    Pathways

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interactome
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