EXOSC3 Protein (AA 1-275) (His tag)
Quick Overview for EXOSC3 Protein (AA 1-275) (His tag) (ABIN7280693)
Target
See all EXOSC3 ProteinsProtein Type
Origin
Source
Application
Purity
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                                            Protein Characteristics
- AA 1-275
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                                            Purification tag / Conjugate
- This EXOSC3 protein is labelled with His tag.
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                                            Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMAEPASV AAESLAGSRA RAARTVLGQV VLPGEELLLP EQEDAEGPGG AVERPLSLNA RACSRVRVVC GPGLRRCGDR LLVTKCGRLR HKEPGSGSGG GVYWVDSQQK RYVPVKGDHV IGIVTAKSGD IFKVDVGGSE PASLSYLSFE GATKRNRPNV QVGDLIYGQF VVANKDMEPE MVCIDSCGRA NGMGVIGQDG LLFKVTLGLI RKLLAPDCEI IQEVGKLYPL EIVFGMNGRI WVKAKTIQQT LILANILEAC EHMTSDQRKQ IFSRLAES
 
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                                            Application Notes
- Optimal working dilution should be determined by the investigator.
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                                            Restrictions
- For Research Use only
 
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                                            Format
- Liquid
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                                            Concentration
- 0.5 mg/mL
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                                            Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 7.5 containing 0.15M NaCl, 30 % glycerol, 1 mM DTT
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                                            Storage
- 4 °C,-20 °C,-80 °C
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                                            Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
 
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    - EXOSC3 (Exosome Component 3 (EXOSC3))
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                                            Alternative Name
- EXOSC3
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                                            Background
- EXOSC3 is a non-catalytic component of the human exosome, a complex with 3'-5' exoribonuclease activity that plays a role in numerous RNA processing and degradation activities. Related pseudogenes of this gene are found on chromosome 19 and 21. Alternatively spliced transcript variants encoding different isoforms have been described. Recombinant human EXOSC3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
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                                            Molecular Weight
- 32.0 kDa (298aa) confirmed by MALDI-TOF
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                                            NCBI Accession
- NP_057126
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                                            UniProt
- Q9NQT5
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                                            Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interactome
 Target
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