IL17B Protein (AA 21-180) (His tag)
Quick Overview for IL17B Protein (AA 21-180) (His tag) (ABIN6387979)
Target
See all IL17B ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 21-180
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Purification tag / Conjugate
- This IL17B protein is labelled with His tag.
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Sequence
- QPRSPKS KRKGQGRPGP LAPGPHQVPL DLVSRMKPYA RMEEYERNIE EMVAQLRNSS ELAQRKCEVN LQLWMSNKRS LSPWGYSINH DPSRIPVDLP EARCLCLGCV NPFTMQEDRS MVSVPVFSQV PVRRRLCPPP PRTGPCRQRA VMETIAVGCT CIF
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Purification
- > 90% by SDS-PAGE
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Endotoxin Level
- < 1 EU per 1ug of protein (determined by LAL method)
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- Phosphate-Buffered Saline ( pH 7.4) containing 10 % glycerol
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Handling Advice
- Avoid repeated freezing and thawing cycles
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- IL17B (Interleukin 17B (IL17B))
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Alternative Name
- IL-17B
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Background
- IL17B, also known as interleukin-17B isoform 1, is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. It plays a role in inflammation and bone growth. IL-17B binds to IL-17 RB and induces the production of inflammatory cytokines and the infiltration of inflammatory immune cells. Recombinant human IL17B protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
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Molecular Weight
- 19.2 kDa (169aa)
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NCBI Accession
- NP_055258
Target
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