CD160 Protein (CD160) (AA 27-159) (His tag)
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- Target See all CD160 Proteins
- CD160
- Protein Type
- Recombinant
- Protein Characteristics
- AA 27-159
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This CD160 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
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INITSSA SQEGTRLNLI CTVWHKKEEA EGFVVFLCKD RSGDCSPETS LKQLRLKRDP GIDGVGEISS QLMFTISQVT PLHSGTYQCC ARSQKSGIRL QGHFFSILFT ETGNYTVTGL KQRQHLEFSH NEGTLS - Purity
- > 90% by SDS-PAGE
- Endotoxin Level
- < 1 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product CD160 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- Target
- CD160
- Alternative Name
- CD160 (CD160 Products)
- Background
- CD160, also known as CD160 antigen, is a human natural killer (NK) -cell-activating receptor that is also expressed on T-cell subsets. It is a tumor-specific antigen known to mediate cellular activation signals in CLL, and is a novel target for therapeutic manipulation and monitoring of minimal residual disease. It was identified as a T cell coinhibitory molecule that interacts with the herpesvirus entry mediator (HVEM) on antigen-presenting cells to deliver a potent inhibitory signal to CD4 (+) T cells. Recombinant human CD160, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 15.9 kDa (142aa)
- NCBI Accession
- NP_008984
- UniProt
- O95971
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