GFRA1 Protein (AA 25-430) (hIgG-His-tag)
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- Target See all GFRA1 Proteins
- GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 25-430
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Origin
- Rat
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This GFRA1 protein is labelled with hIgG-His-tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- DRLDCVKASD QCLKEQSCST KYRTLRQCVA GKETNFSLTS GLEAKDECRS AMEALKQKSL YNCRCKRGMK KEKNCLRIYW SMYQSLQGND LLEDSPYEPV NSRLSDIFRA VPFISDVFQQ VEHISKGNNC LDAAKACNLD DTCKKYRSAY ITPCTTSMSN EVCNRRKCHK ALRQFFDKVP AKHSYGMLFC SCRDIACTER RRQTIVPVCS YEERERPNCL SLQDSCKTNY ICRSRLADFF TNCQPESRSV SNCLKENYAD CLLAYSGLIG TVMTPNYVDS SSLSVAPWCD CSNSGNDLED CLKFLNFFKD NTCLKNAIQA FGNGSDVTMW QPAPPVQTTT ATTTTAFRVK NKPLGPAGSE NEIPTHVLPP CANLQAQKLK SNVSGSTHLC LSDSDFGKDG LAGASSLEPK SCDKTHTCPP CPAPELLGGP SVFLFPPKPK DTLMISRTPE VTCVVVDVSH EDPEVKFNWY VDGVEVHNAK TKPREEQYNS TYRVVSVLTV LHQDWLNGKE YKCKVSNKAL PAPIEKTISK AKGQPREPQV YTLPPSRDEL TKNQVSLTCL VKGFYPSDIA VEWESNGQPE NNYKTTPPVL DSDGSFFLYS KLTVDKSRWQ QGNVFSCSVM HEALHNHYTQ KSLSLSPGKH HHHHH
- Purity
- > 85 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Top Product
- Discover our top product GFRA1 Protein
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GDNF Family Receptor alpha 1 (GFRA1) (AA 25-424) protein (His tag)
GFRA1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
GDNF Family Receptor alpha 1 (GFRA1) (AA 267-360) protein (GST tag)GFRA1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
GDNF Family Receptor alpha 1 (GFRA1) (AA 1-460) protein (GST tag)GFRA1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
GDNF Family Receptor alpha 1 (GFRA1) (Active) protein (His tag)GFRA1 Origin: Mouse Host: HEK-293 Cells Recombinant > 98 % as determined by SDS-PAGE Active
GDNF Family Receptor alpha 1 (GFRA1) (Active) protein (His tag)GFRA1 Origin: Rat Host: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
GDNF Family Receptor alpha 1 (GFRA1) (Active) protein (Fc Tag)GFRA1 Origin: Rat Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
GDNF Family Receptor alpha 1 (GFRA1) (AA 25-429) protein (His tag)Crystallography grade GFRA1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
GDNF Family Receptor alpha 1 (GFRA1) (AA 25-430) protein (His tag)Crystallography grade GFRA1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))
- Alternative Name
- Gfra1 (GFRA1 Products)
- Synonyms
- gdnfr Protein, ret1l Protein, retl1 Protein, trnr1 Protein, gdnfra Protein, MGC122616 Protein, gfr-alpha-1 Protein, GDNFR Protein, GDNFRA Protein, GFR-ALPHA-1 Protein, RET1L Protein, RETL1 Protein, TRNR1 Protein, GDNFRALPHA Protein, GFRA1 Protein, AU042498 Protein, gfralpha1a Protein, zgc:110129 Protein, GDNF family receptor alpha 1 Protein, glial cell line derived neurotrophic factor family receptor alpha 1 Protein, gdnf family receptor alpha 1a Protein, gfra1 Protein, GFRA1 Protein, Gfra1 Protein, gfra1a Protein
- Background
- Gfra1, also known as GDNF family receptor alpha-1, is a member of the GDNF receptor family. It is a glycosyl-phosphatidylinositol(GPI)-linked cell surface receptor for both Glial cell line-derived growth factor (GDNF), neurturin (NTN), and mediates activation of the RET tyrosine kinase receptor. This protein is a potent survival factor for central and peripheral neurons, and is essential for the development of kidneys and the enteric nervous system. Recombinant rat Gfra1 protein, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 72.3kDa (645aa) 70-100KDa (SDS-PAGE under reducing conditions.)
- NCBI Accession
- NP_037091
- UniProt
- Q62997
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