CD247 Protein (AA 52-164) (His tag)
-
- Target See all CD247 Proteins
- CD247 (CD247 Molecule (CD247))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 52-164
-
Origin
- Human
-
Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This CD247 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
-
RVKFSRS ADAPAYQQGQ NQLYNELNLG RREEYDVLDK RRGRDPEMGG KPQRRKNPQE GLYNELQKDK MAEAYSEIGM KGERRRGKGH DGLYQGLSTA TKDTYDALHM QALPPR - Purity
- > 90% by SDS-PAGE
- Endotoxin Level
- < 1 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product CD247 Protein
-
CD247 Molecule (CD247) (AA 62-164) protein (His tag)
CD247 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
CD247 Molecule (CD247) (AA 1-164) protein (GST tag)CD247 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
CD247 Molecule (CD247) proteinCD247 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % pure SDS
CD247 Molecule (CD247) (AA 1-160) protein (His tag)CD247 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, ELISA, WB, IP
CD247 Molecule (CD247) (AA 1-157) protein (His tag)CD247 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, ELISA, WB, IP
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.2 mg/mL
- Buffer
- Liquid. 20 mM Tris-HCl buffer ( pH 6.8) containing 50 % glycerol, 1 mM DTT, 1 mM EDTA, 0.1M NaCl
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
-
- Target
- CD247 (CD247 Molecule (CD247))
- Alternative Name
- CD3 zeta/CD247 (CD247 Products)
- Background
- CD247, also known as T-cell surface glycoprotein CD3 zeta chain isoform 1, belongs to CD3Z / FCER1G family. The T cell receptor Zeta together, with alpha / beta and gamma / delta heterodimers. This Protein plays an important role in binding antigen recognition to multiple intracellular signaling pathways and also plays a role in assembly and expression of the TCR complex. Defects in CD247 defects can cause immune deficiencies. Immune deficiency, characterized by T cells, impaired immune responses to allogeneic antigens, tetanus toxoid and mitogen. Recombinant human CD247, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 14.1 kDa (122aa)
- NCBI Accession
- NP_932170
- UniProt
- P20963
- Pathways
- TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
-
