CD44 Protein (CD44) (AA 21-220) (hIgG-His-tag)
Quick Overview for CD44 Protein (CD44) (AA 21-220) (hIgG-His-tag) (ABIN6388211)
Target
See all CD44 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 21-220
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Purification tag / Conjugate
- This CD44 protein is labelled with hIgG-His-tag.
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Sequence
- QIDLNITCRF AGVFHVEKNG RYSISRTEAA DLCKAFNSTL PTMAQMEKAL SIGFETCRYG FIEGHVVIPR IHPNSICAAN NTGVYILTSN TSQYDTYCFN ASAPPEEDCT SVTDLPNAFD GPITITIVNR DGTRYVQKGE YRTNPEDIYP SNPTDDDVSS GSSSERSSTS GGYIFYTFST VHPIPDEDSP WITDSTDRIP LEPKSCDKTH TCPPCPAPEL LGGPSVFLFP PKPKDTLMIS RTPEVTCVVV DVSHEDPEVK FNWYVDGVEV HNAKTKPREE QYNSTYRVVS VLTVLHQDWL NGKEYKCKVS NKALPAPIEK TISKAKGQPR EPQVYTLPPS RDELTKNQVS LTCLVKGFYP SDIAVEWESN GQPENNYKTT PPVLDSDGSF FLYSKLTVDK SRWQQGNVFS CSVMHEALHN HYTQKSLSLS PGKHHHHHH
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Endotoxin Level
- < 1 EU per 1ug of protein (determined by LAL method)
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CD44 (CD44) (AA 1-699) protein (GST tag)
CD44 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
CD44 (CD44) (AA 152-311) protein (His-IF2DI Tag)CD44 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
CD44 (CD44) (AA 21-220) protein (His tag)CD44 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
CD44 (CD44) (AA 1-361) protein (GST tag)CD44 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
CD44 (CD44) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)CD44 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- CD44
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Alternative Name
- CD44
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Background
- CD44, also known as CD44 antigen isoform 1, is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. The most extensively characterized ligand for CD44 is hyaluronan, a component of the extracellular matrix. It is expressed on the majority of immune cells. The binding of CD44 to hyaluronan is induced on T lymphocytes after activation by antigen and on monocytes after stimulation by inflammatory agents. It improves the prognostic efficacy of tumor differentiation. It might be determinant of differentiation characteristics, imparting properties of increased self-renewal, migration, and invasion. Also it involved in lymphocyte activation, recirculation and homing, and hematopoiesis. Recombinant human CD44, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
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Molecular Weight
- 49 kDa (439aa)
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NCBI Accession
- NP_000601
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UniProt
- P16070
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Pathways
- Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
Target
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