UBE2N Protein (AA 1-152) (His tag)
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- Target See all UBE2N Proteins
- UBE2N (Ubiquitin-Conjugating Enzyme E2N (UBE2N))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-152
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This UBE2N protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- UBE2N, 1-152aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product UBE2N Protein
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Ubiquitin-Conjugating Enzyme E2N (UBE2N) (AA 1-152) protein (GST tag)
UBE2N Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
Ubiquitin-Conjugating Enzyme E2N (UBE2N) (AA 2-152) protein (His tag)UBE2N Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Ubiquitin-Conjugating Enzyme E2N (UBE2N) (AA 1-152) protein (GST tag)UBE2N Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Ubiquitin-Conjugating Enzyme E2N (UBE2N) (AA 1-152) protein (Strep Tag)Crystallography grade UBE2N Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Ubiquitin-Conjugating Enzyme E2N (UBE2N) protein (Myc-DYKDDDDK Tag)UBE2N Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, Q10010.1M NaCl,1mM DTT
- Storage
- 4 °C
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- Target
- UBE2N (Ubiquitin-Conjugating Enzyme E2N (UBE2N))
- Alternative Name
- UBE2N (UBE2N Products)
- Synonyms
- UBC13 Protein, UbcH-ben Protein, UbcH13 Protein, 1500026J17Rik Protein, AL022654 Protein, BB101821 Protein, ube2n Protein, wu:fb11b03 Protein, wu:fc08b06 Protein, zgc:55726 Protein, ubc13 Protein, ubch-ben Protein, UBE2N Protein, ube2nl Protein, zgc:63901 Protein, ubiquitin conjugating enzyme E2 N Protein, ubiquitin-conjugating enzyme E2N Protein, ubiquitin conjugating enzyme E2 N S homeolog Protein, ubiquitin-conjugating enzyme E2Na Protein, ubiquitin-conjugating enzyme E2Nb Protein, UBE2N Protein, Ube2n Protein, ube2n.S Protein, ube2na Protein, LOC100533434 Protein, ube2n Protein, ube2nb Protein
- Background
- UBE2N, also known as UBC13, is a member of the E2 ubiquitin-conjugating enzyme family. It catalyzes the ATP-dependent synthesis of non-canonical polyubiquitin chains, a process that does not lead to proteasomal degradation. It mediates the transcription of several target genes and is thought to play a role in cell cycle progression, cellular differentiation and DNA repair mechanisms that ensure cell survival after DNA damage. Recombinant human UBE2N protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Ubiquitin-conjugating enzyme E2 N, MGC131857, MGC8489, UBC13, UbcH-ben. NCBI no.: NP_003339
- Molecular Weight
- 19.3 kDa(172aa), confirmed by MALDI-TOF
- Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Positive Regulation of Response to DNA Damage Stimulus, Ubiquitin Proteasome Pathway
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