EIF5A Protein (AA 1-154)
Quick Overview for EIF5A Protein (AA 1-154) (ABIN666636)
Target
See all EIF5A ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 1-154
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Characteristics
- eIF5A, 1-154 aa, Human, Recombinant, E.coli
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.0 mg/ml (determined by Bradford assay)
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Buffer
- Liquid. In 50 mM Tris-HCl buffer pH 7.5 containing 10 % glycerol
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Storage
- 4 °C
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- EIF5A (Eukaryotic Translation Initiation Factor 5A (EIF5A))
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Alternative Name
- eIF5A
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Background
- Eukaryotic translation initiation factor 5A (eIF5A) is the only protein Known to contain unusual amino acid formed by the action of deoxyhypusine synthase and deoxyhypusine hydroxylase using spermidine as the substrate. This protein was previously reported to be involved in the first step of peptide bond formation in translation, however more recent work implicates it as a universally conserved translation elongation factor. Modulation of eIF5A has been linked to proliferation and cancer. Recombinant human eIF5A protein was expressed in E. coli and purified by using conventional chromatography techniques. Synonyms: EIF-5A, EIF5A1, eIF5AI, Eukaryotic translation initiation factor 5A isoform B eIF 4D, EIF 5A, eIF 5A 1, eIF 5A1, eIF4D, uORF, uORF A, Eukaryotic initiation factor 5A, Rev binding factor, Eukaryotic initiation factor 5A isoform 1, MGC99547, Eukaryotic translation initiation factor 5A, Eukaryotic translation initiation factor 5A 1, MGC104255. NCBI no.: NP_001961
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Molecular Weight
- 16.8 kDa (154 aa), confirmed by MALDI-TOF.
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Pathways
- Regulation of Muscle Cell Differentiation
Target
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