STIM1 Protein (AA 23-213) (CaM)

Catalog No. ABIN666653

This Recombinant STIM1 protein is produced in Escherichia coli (E. coli).

Quick Overview for STIM1 Protein (AA 23-213) (CaM) (ABIN666653)

Target: STIM1 (Stromal Interaction Molecule 1 (STIM1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 90 % by SDS - PAGE

Product Details

Protein Characteristics: AA 23-213

Purification tag / Conjugate: This STIM1 protein is labelled with CaM.

Characteristics: STIM1, 23-213aa, Human, CaM tagged, Recombinant, E.coli

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid in 20mM Tris pH 7.5

Storage: 4 °C

Target Details

Target: STIM1 (Stromal Interaction Molecule 1 (STIM1))

Alternative Name: STIM1

Background: Stromal interaction molecule 1 (STIM1) is a transmembrane protein that is essential for store-operated Ca(2+) entry, a process of extracellular Ca(2+) influx in response to the depletion of Ca(2+) stores in the endoplasmic reticulum (ER). STIM1 localizes predominantly to the ER, upon Ca(2+) release from the ER, STIM1 translocates to the ER-plasma membrane junctions and activates Ca(2+) channels. Recombinant Calmodulin tagged STIM was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: GOK, D11S4896E, Stromal interaction molecule 1, STIM1, Stromal interaction molecule 1 D11S4896E, SIM, STIM 1, Stim1 stromal interaction molecule 1. NCBI no.: NP_003147

Molecular Weight: 38 kDa (343 aa), confirmed by MALDI-TOF.

Pathways: TCR Signaling, BCR Signaling