Quick Overview for FH Protein (AA 44-510) (ABIN666730)
Target
See all FH ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 44-510
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Characteristics
- Fumarase, 44-510aa, Human, Recombinant, E.coli
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Fumarate Hydratase (FH) (AA 33-510) protein (GST tag)
FH Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Fumarate Hydratase (FH) protein (Myc-DYKDDDDK Tag)FH Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/ml (determined by Bradford assay)
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Buffer
- Liquid. In 20 mM Tris-HCl buffer (pH 8.0)
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Storage
- 4 °C
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- FH (Fumarate Hydratase (FH))
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Alternative Name
- Fumarase
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Background
- Fumarase (Fumarate hytdratase) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to S-malate and is involved in the tricarboxylic acid (TCA), or Krebs cycle. This enzyme exists in both a cytosolic form and an N-terminal extended mitochondrial form. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension is the same form as in the cytoplasm. Fumarase deficiency can lead to progressive encephalopathy, cerebral atrophy and developmental delay and this enzyme also is thought to act as a tumor suppressor. Recombinant Fumarase was expressed in E.coli and was purified by conventional chromatography techniques. Synonyms: FH, HLRCC, LRCC, MCL, MCUL1 , Fumarate hydratase Fumarase, Fumarate hydratase mitochondrial, MCUL 1, Multiple hereditary cutaneous leiomyomata. NCBI no.: NP_000134
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Molecular Weight
- 50.2kDa (467aa), confirmed by MALDI-TOF.
Target
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