BMP4 Protein (AA 293-408)

Catalog No. ABIN666737

This Recombinant BMP4 protein is produced in Escherichia coli (E. coli).

Quick Overview for BMP4 Protein (AA 293-408) (ABIN666737)

Target: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 95 % by SDS - PAGE

Product Details

Protein Characteristics: AA 293-408

Characteristics: BMP- 4, 293-408aa, Human, Recombinant, E.coli

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 10mM Sodium citrate buffer (pH 3.5), 10% glycerol

Storage: 4 °C

Target Details

Target: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Alternative Name: BMP- 4

Background: Bone morphogenetic protein 4 (BMP-4) is a member of the bone morphogenetic protein family which belongs to the TGF-beta superfamily. This protein is a vital regulatory molecule that functions throughout bone and cartilage development, specifically tooth development, limb formation, bone induction, and fracture repair. In human embryonic development, BMP- 4 is required for the early differentiation of the embryo and establishing of a dorsal-ventral axis. And it is overexpressed in patients with fibrodysplasia ossificans progressiva. Recombinant BMP-4 was expressed as insoluble protein aggregate in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. Synonyms: BMP-2B, DVR4, Bone morphogenetic protein 4 BMP 4, BMP2B, BMP2B1, ZYME, BMP4. NCBI no.: NP_001193

Molecular Weight: 13.2 kDa (117 aa), confirmed by MALDI-TOF.

Pathways: Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development