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CCL3 Protein (AA 24-92) (His tag)

CCL3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90% by SDS-PAGE SDS
Catalog No. ABIN666794
  • Target See all CCL3 Proteins
    CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 24-92
    Origin
    • 17
    • 8
    • 7
    • 3
    • 1
    • 1
    • 1
    Human
    Source
    • 26
    • 4
    • 3
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This CCL3 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    SLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPGV IFLTKRSRQV CADPSEEWVQ KYVSDLELSA
    Characteristics
    CCL3, 24-92aa, Human, His tag, E.coli
    Purity
    > 90% by SDS-PAGE
    Endotoxin Level
    < 1 EU per 1ug of protein (determined by LAL method)
    Top Product
    Discover our top product CCL3 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    Liquid. In 10mM Sodium Citrate ( pH3.5) containing 10% glycerol
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
  • Target
    CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))
    Alternative Name
    CCL3/MIP-1 alpha (CCL3 Products)
    Background
    CCL3, also known as, macrophage inflammatory protein-1alpha (MIP-1alpha), is a cytokine belonging to the CC chemokine family that is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes. This protein has been identified as one of the major HIV-SFs produced by CD8+ T cells, along with MIP-1beta and RANTES. It acts as an inhibitor of different strains of HIV-1, HIV-2 and SIV infection in a dose-dependent manner. Recombinant human CCL3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
    Molecular Weight
    10 kDa (90aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
    NCBI Accession
    NP_002974
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Autophagy
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