alpha Synuclein E46K (AA 1-140) Protein

Catalog No. ABIN666821

This Recombinant alpha Synuclein E46K protein is produced in Escherichia coli (E. coli).

Quick Overview for alpha Synuclein E46K (AA 1-140) Protein (ABIN666821)

Target: alpha Synuclein E46K

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 95 %

Product Details

Protein Characteristics: AA 1-140

Sequence: MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKKGVVH GVATVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGSIAA ATGFVKKDQL GKNEEGAPQE GILEDMPVDP DNEAYEMPSE EGYQDYEPEA

Characteristics: alpha-Synuclein E46K, Human, Recomninant, E.coli

Purification: > 95% by SDS-PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 20 mM Tris-HCl buffer ( pH 7.5) containing 0.1M NaCl

Handling Advice: Avoid repeated freezing and thawing cycles

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details

Target: alpha Synuclein E46K

Alternative Name: alpha-Synuclein E46K

Background: Alpha-Synuclein E46K is a mutant form of alpha-synuclein which is changed at position 46 from glutamate (E) to lysine (K). Recent studies have shown that this mutant (E46K) of alpha-synuclein causes Parkinson and Lewy Body dementia (DLB). alpha-Synuclein E46K was overexpressed in E. coli and purified to apparent homogeneity by using conventional column chromatography techniques

Molecular Weight: 14.4 (140aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

NCBI Accession: NP_000336