TTR Protein (AA 21-147)

Catalog No. ABIN666931

Recombinant TTR protein expressed in Escherichia coli (E. coli).

Quick Overview for TTR Protein (AA 21-147) (ABIN666931)

Target: TTR (Transthyretin (TTR))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 95 % by SDS - PAGE

Product Details

Protein Characteristics: AA 21-147

Characteristics: Prealbumin, 21-147aa, Human, E.coli

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol

Storage: 4 °C

Target Details

Target: TTR (Transthyretin (TTR))

Alternative Name: Prealbumin

Background: Prealbumin, also known Transthyretin, is a tetrameric human plasma protein that is synthesized mainly in the liver. This protein transports the thyroid hormone thyroxine (T4) and retinol (Vitamin A). It is the best indicator of protein-energy malnutrition because it has a circulating half life of 2 days and responds rapidly to changes in nutritional status. Also point-mutations of its gene are known to be associated with the amyloid diseases senile systemic amyloidosis (SSA), familial amyloid polyneuropathy (FAP), and familial amyloid cardiomyopathy (FAC). Recombinant human Prealbumin was expressed in E.coli and purified by using conventional chromatography. Synonyms: TTR, Transthyretin, TBPA, ATTR, PALB, Amyloid polyneuropathy, Amyloidosis I, Dysprealbuminemic euthyroidal hyperthyroxinemia, Dystransthyretinemic hyperthyroxinemia, HsT2651, Prealbumin amyloidosis type I, Senile systemic amyloidosis, TTR protein. NCBI no.: NP_000362

Molecular Weight: 13.8 kDa (128aa), confirmed by MALDI-TOF.

Pathways: Hormone Transport