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OAT Protein (AA 33-439)

This Recombinant OAT protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN666933

Quick Overview for OAT Protein (AA 33-439) (ABIN666933)

Target

See all OAT Proteins
OAT (Ornithine Aminotransferase (OAT))

Protein Type

Recombinant

Origin

  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Source

  • 5
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Application

SDS-PAGE (SDS)

Purity

> 90 % by SDS - PAGE
  • Protein Characteristics

    AA 33-439

    Characteristics

    OAT, 33-439aa, Human, E.coli
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  • Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1.0 mg/ml (determined by Bradford assay)

    Buffer

    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol

    Storage

    4 °C
  • Target

    OAT (Ornithine Aminotransferase (OAT))

    Alternative Name

    OAT

    Background

    OAT, also known as mitochondrial enzyme ornithine aminotransferase, is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. ( L-ornithine + a 2-oxo acid = L-glutamate 5-semialdehyde + an L-amino acid.) Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Recombinant OAT protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: DKFZp781A11155, HOGA, OATASE, ornithine aminotransferase precursor EC 2.6.1.13, ornithine aminotransferase (gyrate atrophy), ornithine aminotransferase precursor, Ornithine aminotransferase, mitochondrial precursor, Ornithine oxo-acid aminotransferase, Ornithine--oxo-acid aminotransferase. NCBI no.: NP_000265

    Molecular Weight

    45.2 kDa (408aa), confirmed by MALDI-TOF.
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