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Aurora A Protein (AA 1-403) (His tag)

AURKA Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85% by SDS-PAGE SDS
Catalog No. ABIN667117
  • Target See all Aurora A (AURKA) Proteins
    Aurora A (AURKA) (Aurora Kinase A (AURKA))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-403
    Origin
    • 10
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Source
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This Aurora A protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    MDRSKENCIS GPVKATAPVG GPKRVLVTQQ FPCQNPLPVN SGQAQRVLCP SNSSQRIPLQ AQKLVSSHKP VQNQKQKQLQ ATSVPHPVSR PLNNTQKSKQ PLPSAPENNP EEELASKQKN EESKKRQWAL EDFEIGRPLG KGKFGNVYLA REKQSKFILA LKVLFKAQLE KAGVEHQLRR EVEIQSHLRH PNILRLYGYF HDATRVYLIL EYAPLGTVYR ELQKLSKFDE QRTATYITEL ANALSYCHSK RVIHRDIKPE NLLLGSAGEL KIADFGWSVH APSSRRTTLC GTLDYLPPEM IEGRMHDEKV DLWSLGVLCY EFLVGKPPFE ANTYQETYKR ISRVEFTFPD FVTEGARDLI SRLLKHNPSQ RPMLREVLEH PWITANSSKP SNCQNKESAS KQS
    Characteristics
    Aurora kinase A, 1-403aa, Human, His-tagged, Recombinant, E.coli
    Purity
    > 85% by SDS-PAGE
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  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 0.5mM DTT, 100mM NaCl, 0.1mM EDTA, 0.1mM EGTA, 0.1mM PMSF, 20% glycerol.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
  • Target
    Aurora A (AURKA) (Aurora Kinase A (AURKA))
    Alternative Name
    Aurora A (AURKA Products)
    Background
    Aurora Kinase A is a member of a family of mitotic serine/threonine kinases. It is implicated with important processes during mitosis and meiosis whose proper function is integral for healthy cell proliferation. Aurora kinase A is highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also this protein plays a crucial role in tumourigenesis and is overexpressed in many kinds of cancers. Recombinant human Aurora-A fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
    Molecular Weight
    47.9 kDa (423aa)
    NCBI Accession
    NP_003591
    Pathways
    Cell Division Cycle, Asymmetric Protein Localization
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