Nanog Protein (AA 1-305)
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- Target See all Nanog (NANOG) Proteins
- Nanog (NANOG) (Nanog Homeobox (NANOG))
- Protein Characteristics
- AA 1-305
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Characteristics
- NANOG, 1-305aa, Human, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product NANOG Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 5% glycerol
- Storage
- 4 °C
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- Target
- Nanog (NANOG) (Nanog Homeobox (NANOG))
- Alternative Name
- NANOG (NANOG Products)
- Background
- Nanog homeobox, also known as nanog, is a member of the homeobox family of DNA binding transcription factors that has been shown to maintain pluripotency of embryonic stem cells. Nanog expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF, Stat3 and BMP. Once NANOG expression is downregulated, cell differentiation can proceed. Proteins which regulate NANOG expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53. Synonyms: Nanog homeobox, Homeobox transcription factor Nanog, homeobox transcription factor Nanog-delta 48. NCBI no.: NP_079141
- Molecular Weight
- 34.6 kDa (305aa)
- Pathways
- Stem Cell Maintenance
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