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Nanog Protein (AA 1-305)

Nanog protein expressed in Escherichia coli (E. coli).
Catalog No. ABIN667504

Quick Overview for Nanog Protein (AA 1-305) (ABIN667504)

Target

See all Nanog (NANOG) Proteins
Nanog (NANOG) (Nanog Homeobox (NANOG))

Origin

  • 11
  • 2
  • 1
  • 1
Human

Source

  • 9
  • 2
  • 2
  • 2
Escherichia coli (E. coli)

Application

SDS-PAGE (SDS)

Purity

> 90 % by SDS - PAGE
  • Protein Characteristics

    AA 1-305

    Characteristics

    NANOG, 1-305aa, Human, E.coli
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  • Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/ml (determined by Bradford assay)

    Buffer

    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 5% glycerol

    Storage

    4 °C
  • Target

    Nanog (NANOG) (Nanog Homeobox (NANOG))

    Alternative Name

    NANOG

    Background

    Nanog homeobox, also known as nanog, is a member of the homeobox family of DNA binding transcription factors that has been shown to maintain pluripotency of embryonic stem cells. Nanog expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF, Stat3 and BMP. Once NANOG expression is downregulated, cell differentiation can proceed. Proteins which regulate NANOG expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53. Synonyms: Nanog homeobox, Homeobox transcription factor Nanog, homeobox transcription factor Nanog-delta 48. NCBI no.: NP_079141

    Molecular Weight

    34.6 kDa (305aa)

    Pathways

    Stem Cell Maintenance
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