COPS8 Protein (AA 1-209) (His tag)
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- Target See all COPS8 Proteins
- COPS8 (COP9 Signalosome Subunit 8 (COPS8))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-209
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This COPS8 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- COPS8, 1-209aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol
- Storage
- 4 °C
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- Target
- COPS8 (COP9 Signalosome Subunit 8 (COPS8))
- Alternative Name
- COPS8 (COPS8 Products)
- Background
- COP9 signalosome complex subunit 8 isoform 1, also known as COPS8, is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Recombinant human COPS8 protein, fused to His-tag at N-terminus, was expressed in E.coli. Synonyms: COP9 signalosome complex subunit 8, COP9, CSN8, SGN8. NCBI no.: NP_006701
- Molecular Weight
- 25.3 kDa (229aa)
- Pathways
- Cell Division Cycle
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