DIABLO Protein (AA 56-239) (T7 tag)

Catalog No. ABIN667710

This Recombinant DIABLO protein is expressed in Escherichia coli (E. coli).

Quick Overview for DIABLO Protein (AA 56-239) (T7 tag) (ABIN667710)

Target: DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 95 % by SDS - PAGE

Product Details

Protein Characteristics: AA 56-239

Purification tag / Conjugate: This DIABLO protein is labelled with T7 tag.

Characteristics: SMAC/Diablo, 56-239aa, Human, T7 tagged, Recombinant, E.coli

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid in 20mM Tris pH 7.5

Storage: 4 °C

Target Details

Target: DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))

Alternative Name: SMAC/Diablo

Background: Smac/Diablo is one of the proapoptotic proteins. Smac promotes caspase activation in the cytochrome c/Apaf-1/caspase-9 pathway by binding to inhibitor of apoptosis proteins (IAPs) and removing their inhibitory activity. Recombinant human Smac fused to T7-tag. at N-terminus was expressed in E.coli and purified by conventional chromatography techniques. Synonyms: SMAC3, DIABLO-S, FLJ10537, FLJ25049, Diablo isoform 1, SMAC/Diablo, Diablo isoform 1 0610041G12Rik, DBOH, Diablo homolog, DIABLO S, Diablo homolog (Drosophila), Mitochondrial Smac protein, Diablo homolog mitochondrial, SMAC 3, Smac protein, Direct IAP binding protein with low pI, Second mitochondria derived activator of caspase. NCBI no.: NP_063940

Molecular Weight: 22 kDa (199 aa), confirmed by MALDI-TOF.

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity