GDF10 Protein (AA 369-478)

Catalog No. ABIN667742

Product Details

Target: GDF10 (Growth Differentiation Factor 10 (GDF10))

Protein Type: Recombinant

Protein Characteristics: AA 369-478

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Sequence: MQWDEPRVCS RRYLKVDFAD IGWNEWIISP KSFDAYYCAG ACEFPMPKIV RPSNHATIQS IVRAVGIIPG IPEPCCVPDK MNSLGVLFLD ENRNVVLKVY PNMSVDTCAC R

Characteristics: GDF-10, 369-478 aa, Human, Recombinant, E.coli

Purity: > 95% by SDS-PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid. In 10 mM sodium citrate (pH 3.5) containing 10% glycerol.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Target Details

Target: GDF10 (Growth Differentiation Factor 10 (GDF10))

Alternative Name: BMP-3b/GDF-10 (GDF10 Products)

Background: GDF10 (Growth differentiation factor 10) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It is expressed in femur, brain, lung, skeletal, muscle, pancreas and testis, and it plays a role in head formation and may have multiple roles in skeletal morphogenesis. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Recombinant GDF10 protein was expressed in E. coli and purified by using conventional chromatography techniques.

Molecular Weight: 12.5 kDa (111aa) confirmed by MALDI-TOF

NCBI Accession: NP_004953