EIF2S1 Protein (AA 1-315) (His tag)
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- Target See all EIF2S1 Proteins
- EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-315
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This EIF2S1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- EIF2S1, 1-315aa, Human, His tag, E.coli
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product EIF2S1 Protein
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Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (AA 1-315) protein (His tag)
custom-made EIF2S1 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (AA 1-315) protein (GST tag)EIF2S1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (AA 1-315) protein (His tag)custom-made EIF2S1 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) protein (Myc-DYKDDDDK Tag)EIF2S1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl
- Storage
- 4 °C
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- Target
- EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))
- Alternative Name
- EIF2S1 (EIF2S1 Products)
- Background
- EIF2S1, also known as eIF2 alpha, is the alpha subunit of the translation initiation factor eIF2 complex which catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. The phosphorylation state of eIF2S1 controls the rate of tRNA translation. When eIF2 alpha is not phosphorylated, translation occurs at a normal rate. However, upon phosphorylation by one of several kinases, eIF2S1 is stabilized, thus preventing the GDP/GTP exchange reaction and slowing translation. Recombinant human EIF2S1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: EIF-2, EIF-2A, EIF-2alpha, EIF2, EIF2A, Eukaryotic translation initiation factor 2 subunit 1 EIF 2 alpha, EIF 2, EIF 2A, EIF 2alpha, EIF2 alpha, Eukaryotic translation initiation factor 2 subunit 1 alpha 35kDa, Eukaryotic translation initiation factor 2 subunit 1 alpha, # Eukaryotic translation initiation factor 2 subunit alpha. NCBI no.: NP_004085
- Molecular Weight
- 38.2 kDa (335aa) confirmed by MALDI-TOF
- Pathways
- Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C
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