RAN Protein (AA 1-216) (His tag)
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- Target See all RAN Proteins
- RAN (RAN, Member RAS Oncogene Family (RAN))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-216
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This RAN protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MAAQGEPQVQ FKLVLVGDGG TGKTTFVKRH LTGEFEKKYV ATLGVEVHPL VFHTNRGPIK FNVWDTAGQE KFGGLRDGYY IQAQCAIIMF DVTSRVTYKN VPNWHRDLVR VCENIPIVLC GNKVDIKDRK VKAKSIVFHR KKNLQYYDIS AKSNYNFEKP FLWLARKLIG DPNLEFVAMP ALAPPEVVMD PALAAQYEHD LEVAQTTALP DEDDDL
- Characteristics
- RAN, 1-216aa, Human, His tag, E.coli
- Purity
- > 90% by SDS-PAGE
- Top Product
- Discover our top product RAN Protein
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RAN, Member RAS Oncogene Family (RAN) (AA 1-216) protein (GST tag)
RAN Origin: Human Host: Wheat germ Recombinant ELISA, AP, AA, WB
RAN, Member RAS Oncogene Family (RAN) (AA 2-219) protein (His-SUMO Tag)RAN Origin: Saccharomyces cerevisiae Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
RAN, Member RAS Oncogene Family (RAN) protein (Myc-DYKDDDDK Tag)RAN Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- Target
- RAN (RAN, Member RAS Oncogene Family (RAN))
- Alternative Name
- RAN (RAN Products)
- Background
- RAN, member RAS oncogene family, also known as RAN, is a small GTPase of the Ras superfamily that controls nucleocytoplasmic transport. It is involved in the directionality of the process that is regulated by GTP hydrolysis. Ran shuttles between the nucleus and the cytoplasm. unlike many other regulatory GTPases, Ran is not posttranslationally modified so that it can be targeted to the subcellular compartment where it acts. Rather, RanGTP has been thought to be localized by the differential localization of Ran regulators. Recombinant human RAN, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques
- Molecular Weight
- 26.5 kDa (236aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_006316
- Pathways
- Regulatory RNA Pathways, Intracellular Steroid Hormone Receptor Signaling Pathway, Protein targeting to Nucleus
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