RAN Protein (AA 2-219) (His-SUMO Tag)
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- Target See all RAN Proteins
- RAN (RAN, Member RAS Oncogene Family (RAN))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 2-219
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Origin
- Saccharomyces cerevisiae
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This RAN protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- SAPAANGEVP TFKLVLVGDG GTGKTTFVKR HLTGEFEKKY IATIGVEVHP LSFYTNFGEI KFDVWDTAGQ EKFGGLRDGY YINAQCAIIM FDVTSRITYK NVPNWHRDLV RVCENIPIVL CGNKVDVKER KVKAKTITFH RKKNLQYYDI SAKSNYNFEK PFLWLARKLA GNPQLEFVAS PALAPPEVQV DEQLMQQYQQ EMEQATALPL PDEDDADL
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product RAN Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- RAN (RAN, Member RAS Oncogene Family (RAN))
- Alternative Name
- GSP1 (RAN Products)
- Synonyms
- ARA24 Protein, Gsp1 Protein, TC4 Protein, ran Protein, ara24 Protein, gsp1 Protein, ran-1 Protein, tc4 Protein, RAN Protein, RANP1 Protein, AAF30287 Protein, CG1404 Protein, Dmel\CG1404 Protein, Ran Protein, dran Protein, l(1)G0075 Protein, ran10A Protein, fc16b04 Protein, wu:fc16b04 Protein, RAN, member RAS oncogene family Protein, RAN, member RAS oncogene family S homeolog Protein, CG1404 gene product from transcript CG1404-RC Protein, RAN Protein, Ran Protein, ran.S Protein, ran Protein
- Background
- GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Essential for cell viability. By analogy with Ras, Ran may be activated when GTP is exchanged for bound GDP by RCC1 and inactivated when GTP is hydrolyzed by Ran upon activation by RanGAP1.
- Molecular Weight
- 40.66 kDa
- UniProt
- P32835
- Pathways
- Regulatory RNA Pathways, Intracellular Steroid Hormone Receptor Signaling Pathway, Protein targeting to Nucleus
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