BST2 Protein (AA 50-161) (His tag)
Quick Overview for BST2 Protein (AA 50-161) (His tag) (ABIN667927)
Target
See all BST2 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 50-161
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Purification tag / Conjugate
- This BST2 protein is labelled with His tag.
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Sequence
- MGSSHHHHHH SSGLVPRGSH MSEACRDGLR AVMECRNVTH LLQQELTEAQ KGFQDVEAQA ATCNHTVMAL MASLDAEKAQ GQKKVEELEG EITTLNHKLQ DASAEVERLR RENQVLSVRI ADKKYYPSSQ DSS
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Characteristics
- BST2, 50-161aa, Human, His tag, E.coli
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Purification
- > 80% by SDS-PAGE
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Bone Marrow Stromal Cell Antigen 2 (BST2) (AA 49-161) (Active) protein (hFc Tag)
BST2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Bone Marrow Stromal Cell Antigen 2 (BST2) (AA 52-152) (Active) protein (hFc Tag)BST2 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Bone Marrow Stromal Cell Antigen 2 (BST2) (AA 52-152) (Active) protein (His tag)BST2 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Bone Marrow Stromal Cell Antigen 2 (BST2) (AA 40-180) protein (GST tag)BST2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Bone Marrow Stromal Cell Antigen 2 (BST2) (AA 1-180) protein (GST tag)BST2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Bone Marrow Stromal Cell Antigen 2 (BST2) (AA 49-163) (Active) protein (His tag)BST2 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Bone Marrow Stromal Cell Antigen 2 (BST2) (AA 99-330) protein (Fc Tag)BST2 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Bone Marrow Stromal Cell Antigen 2 (BST2) protein (Fc Tag)BST2 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- 20 mM Tris-HCl buffer ( pH 8.0) containing 20 % glycerol, 0.1M NaCl, 1 mM DTT
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))
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Alternative Name
- BST-2/Tetherin
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Background
- BST2, also known as bone marrow stromal antigen 2, is involved in the growth and development of B-cells. BST2 is a human cellular protein which inhibits retrovirus infection by preventing the diffusion of virus particles after budding from infected cells. Initially discovered as an inhibitor to HIV-1 infection in the absence of Vpu, tetherin has also been shown to inhibit the release of other viruses such as the Lassa and Marburg virions. Also, this protein may play a role in B-cell activation in rheumatoid arthritis. Recombinant human BST2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
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Molecular Weight
- 14.8 kDa (133aa) confirmed by MALDI-TOF
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NCBI Accession
- NP_004326
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Pathways
- Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response
Target
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