NQO1 Protein (AA 1-274) (His tag)

Catalog No. ABIN668043

This Recombinant NQO1 protein is expressed in Escherichia coli (E. coli).

Quick Overview for NQO1 Protein (AA 1-274) (His tag) (ABIN668043)

Target: NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 95 % by SDS-PAGE

Product Details

Protein Characteristics: AA 1-274

Purification tag / Conjugate: This NQO1 protein is labelled with His tag.

Characteristics: NQO1, 1-274 aa, Human, His-tagged, Recombinant, E.coli

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCL buffer (pH 8.0) containing 10% glycerol 1mM DTT.

Storage: 4 °C

Target Details

Target: NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))

Alternative Name: NQO1

Background: NQO1 is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This protein apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. NQO1 functions as an important part of cellular antioxidant defense by detoxifying quinines thus preventing the formation of reactive oxygen species. Altered expression of NQO1 has been seen in many tumors and is also associated with Alzheimer’s disease (AD). Recombinant NQO1 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: DHQU, DIA4, DTD, NMOR1, NMORI, QR1, Azoreductase, Quinone reductase 1, DT-diaphorase, NAD(P)H dehydrogenase, quinone 1, Azoreductase.Menadione reductase, NQO 1, QR 1, Phylloquinone reductase, Cytochrome b 5 reductase, DIA 4, Diaphorase (NADH/NADPH), Diaphorase 4 Dioxin inducible 1, DT diaphorase, Diaphorase (NADH/NADPH) (cytochrome b 5 reductase), NAD(P)H dehydrogenase quinone 1 NAD(P)H menadione oxidoreductase 1 dioxin inducible, NAD(P)H: menadione oxidoreductase 1 dioxin inducible 1, NAD(P)H:menadione oxidoreductase 1, NAD(P)H:Quinone acceptor oxidoreductase type 1, NAD(P)H:quinone oxidoreductase 1, NAD(P)H:quinone oxireductase, NMOR 1, NMOR I. NCBI no.: NP_000894

Molecular Weight: 33.0 kDa (294aa), confirmed by MALDI-TOF.