CCL20 Protein

Catalog No. ABIN6699617

Supplier Product No.: 009-001-b51

This Recombinant CCL20 protein is expressed in Escherichia coli (E. coli).

Quick Overview for CCL20 Protein (ABIN6699617)

Target: CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: 97,00%

Product Details

Supplier Product No.: 009-001-b51

Supplier: Rockland

Purpose: MIP-3α Human Recombinant Protein

Purification: Purity was determined to be greater than 97% by analysis by RP-HPLC and by reducing and non-reducing SDS-PAGE.

Endotoxin Level: Measured by LAL is < 0.01 ng/μg or < 0.1 EU/μg protein.

Biological Activity Comment: Human MIP-3-alpha is a chemoattractant to human T-cells, working in a concentration range of 7 - 70 ng/ml.

Application Details

Application Notes:

Application Note: MIP-3α protein has been tested by SDS-PAGE and is suitable as a control for polyclonal or monoclonal anti-MIP-3α in immunological assays.

Other: User Optimized

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution:

Reconstitution_Buffer: Restore with deionized water (or equivalent)

Reconstitution_Volume: 20 μL (20-200 μL)

Concentration: 0.1 mg/mL

Buffer:

Buffer: 0.1 % Trifluoroacetic acid

Stabilizer: None

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL) . For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.

Expiry Date: 6 months

Target Details

Target: CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))

Alternative Name: CCL20

Background:

Synonyms: Human Macrophage Inflammatory Protein-3-alpha, CCL20, Small-inducible cytokine A20, Macrophage inflammatory protein 3 alpha, MIP-3-alpha, Liver and Activation-Regulated Chemokine, CC chemokine LARC, Beta-chemokine exodus-1

Background: Human Macrophage Inflammatory Protein-3 alpha, also known as LARC (Liver and Activation Regulated Chemokine) or CCL20. This protein is strongly up regulated by inflammatory signals and down regulated by the anti-inflammatory cytokine IL-10. H-MIP-3-alpha is a non-glycosylated polypeptide chain consisting of 70 amino acids and a molecular weight of 8.0 kDa.

UniProt: P78556

Pathways: The Global Phosphorylation Landscape of SARS-CoV-2 Infection