IL-22 Protein

Catalog No. ABIN6700089

Supplier Product No.: 009-001-j33-0100

Recombinant IL-22 protein expressed in Escherichia coli (E. coli).

Quick Overview for IL-22 Protein (ABIN6700089)

Target: IL-22 (IL22) (Interleukin 22 (IL22))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: 97,00%

Product Details

Supplier Product No.: 009-001-j33-0100

Supplier: Rockland

Purpose: Human Interleukin-22 Recombinant Protein

Purification: Interleukin-22 purity was determined to be greater than 97% as determined by HpLC, analysis by UV-Spectroscopy at 280nm, and by reducing and non-reducing SDS-pAGE.

Endotoxin Level: Measured by LAL is typically ≤ 1 EU/μg protein.

Biological Activity Comment: The activity is determined by the dose-dependent co-stimulation of MC/9 cells in the presence of IL-4 and is typiclly less than 2.0 ng/mL.

Application Details

Application Notes:

Application Note: Interleukin-22 Recombinant Protein has been tested by SDS-PAGE and is suitable as a control for polyclonal or monoclonal anti-Interleukin-22 in immunological assays.

Other: User Optimized

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution:

Reconstitution_Buffer: Restore with deionized water (or equivalent)

Reconstitution_Volume: 100 μL

Buffer:

Buffer: 0.01 M Sodium Citrate, pH 3.0

Stabilizer: None

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.

Expiry Date: 6 months

Target Details

Target: IL-22 (IL22) (Interleukin 22 (IL22))

Alternative Name: IL22

Background:

Synonyms: IL-10-related T-cell-derived-inducible factor (IL-TIF)

Background: Interleukin-22 (IL-22), also called IL-TIF, is an IL-10 family member, produced by activated dendritic cells and T lymphocytes. IL-22 signals via the IL-22R and IL-10Rbeta receptors to act as a potent mediator of the cellular inflammatory response. Recombinant human IL-22 is a non-disulfide-linked homodimer, containing two 146 amino acids, with a total molecular weight of 33.6 kDa.

UniProt: Q9GZX6