IFNA2 Protein

Catalog No. ABIN6700937

Supplier Product No.: 009-001-v19-1000

This Recombinant IFNA2 protein is expressed in Escherichia coli (E. coli).

Quick Overview for IFNA2 Protein (ABIN6700937)

Target: IFNA2 (Interferon, alpha 2 (IFNA2))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: 98,00%

Product Details

Supplier Product No.: 009-001-v19-1000

Supplier: Rockland

Purpose: Human Interferon-alpha 2b Recombinant Protein

Purification: Interferon-alpha 2b purity was determined to be greater than 98% as determined by HpLC and by reducing and non-reducing SDS-pAGE.

Endotoxin Level: Measured by LAL is typically ≤ 1 EU/μg protein.

Biological Activity Comment: The activity is determined by the ability induce antiviral activity.

Application Details

Application Notes:

Application Note: Interferon-alpha 2b Recombinant Protein has been tested by SDS-PAGE and is suitable as a control for polyclonal or monoclonal anti-Interferon-alpha 2b in immunological assays.

Other: User Optimized

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution:

Reconstitution_Buffer: Restore with deionized water (or equivalent)

Reconstitution_Volume: 1.0 mL

Concentration: 0.1 mg/mL

Buffer:

Buffer: None

Stabilizer: None

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.

Expiry Date: 6 months

Target Details

Target: IFNA2 (Interferon, alpha 2 (IFNA2))

Alternative Name: IFNA2

Background:

Synonyms: Interferon alpha-A (LeIF A)Type I Interferon, Alpha 2

Background: Interferon-alpha 2b (IFNα 2b) is a Type I interferon made by leukocytes during viral infection. It has anti-viral and non-proliferative activity induced by JAK1-STAT signaling. IFN-alphas are the most widely used type for therapeutic purposes. IFNα 2b is a variant of IFNα 2a that differs by one amino acid. Recombinant human IFNα 2b is a non-glycosylated protein, containing 166 amino acids, with a molecular weight of 19.4 kDa.

UniProt: P01563

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Hepatitis C