HHLA2 Protein (AA 23-344) (Fc Tag)
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- Target See all HHLA2 Proteins
- HHLA2 (HERV-H LTR-Associating 2 (HHLA2))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 23-344
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This HHLA2 protein is labelled with Fc Tag.
- Sequence
- AA 23-344
- Purity
- >90 % as determined by reduced SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product HHLA2 Protein
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HERV-H LTR-Associating 2 (HHLA2) (AA 23-344) protein (His tag)
HHLA2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
HERV-H LTR-Associating 2 (HHLA2) (AA 23-344) protein (Fc Tag)HHLA2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
HERV-H LTR-Associating 2 (HHLA2) (AA 1-414) protein (GST tag)HHLA2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
HERV-H LTR-Associating 2 (HHLA2) (AA 23-344) (Active) protein (Fc Tag,AVI tag,Biotin)HHLA2 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
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- Target
- HHLA2 (HERV-H LTR-Associating 2 (HHLA2))
- Alternative Name
- B7-H7 (HHLA2 Products)
- Synonyms
- B7H7 Protein, HERV-H LTR-associating 2 Protein, HHLA2 Protein, hhla2 Protein
- Background
- B7-H7 (HHLA2) is a newly identified B7 family member that regulates human T-cell functions. B7-H7 was previously known as human endogenous retrovirus-H long terminal repeat associating 2 (HHLA2) with unidentified function. Recently, B7-H7 has been identified as a specific ligand for human CD28H. The B7-H7-CD28H pathway strongly promoted CD4+ T-cell proliferation and cytokine production via an AKT-dependent signaling cascade in the presence of TCR signaling, suggesting B7-H7 comprises a new co-stimulatory pathway. The first IgV domain of B7-H7, which presumably binds to a putative receptor, shows the highest homology to other B7 family members.
- Molecular Weight
- 63.4 kDa
- NCBI Accession
- NP_009003
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