CD28H (AA 23-150) (Active) protein (His tag)
Quick Overview for CD28H (AA 23-150) (Active) protein (His tag) (ABIN6809929)
Target
Protein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 23-150
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Purification tag / Conjugate
- His tag
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Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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CD28H (AA 23-150) (Active) protein (hFc Tag)
Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD28H (AA 23-150) (Active) protein (His tag)Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Storage
- -20 °C
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- CD28H
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Background
- CD28 homolog (CD28H), also called transmembrane and immunoglobulin domain containing 2 (TMIGD2) and IGPR-1,is encoded by the TMIGD2 gene. CD28H is constitutively expressed on naive T and NK cells. After interaction of CD28 homolog with B7 homologue,the peripheral effector and memory T cells can be activated and proliferated by Akt-dependent signalling cascade. Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.
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Molecular Weight
- 15.9 kDa
Target
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