IL-13 Protein (AA 21-132) (Fc Tag)
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- Target See all IL-13 (IL13) Proteins
- IL-13 (IL13) (Interleukin 13 (IL13))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 21-132
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IL-13 protein is labelled with Fc Tag.
- Purity
- >90 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product IL13 Protein
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Interleukin 13 (IL13) (AA 21-132) protein (His-Avi Tag)
IL13 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Tris-Bis PAGE
Interleukin 13 (IL13) (AA 21-132) protein (Fc Tag)IL13 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 13 (IL13) (AA 19-132) protein (His tag)IL13 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 13 (IL13) (AA 19-132) (Active) proteinIL13 Origin: Human Host: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Interleukin 13 (IL13) (AA 26-131) (Active) protein (His tag)IL13 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE Active
Interleukin 13 (IL13) protein (His-Avi Tag,Biotin)IL13 Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE
Interleukin 13 (IL13) (AA 21-132) (Active) protein (His tag)IL13 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 13 (IL13) (AA 21-132) (Active) protein (His tag,AVI tag,Biotin)IL13 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 13 (IL13) protein (mFc Tag)IL13 Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Interleukin 13 (IL13) (AA 22-131) protein (His tag)IL13 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
- Storage
- -20 °C
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- Target
- IL-13 (IL13) (Interleukin 13 (IL13))
- Alternative Name
- IL-13 (IL13 Products)
- Background
- Interleukin 13 (IL13) is also known as ALRH, BHR1and P600, is a single-chain glycosylated polypeptide, and is a cytokine critical in regulating inflammatory and immune responses. IL13 is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains. The functions of IL-13 overlap considerably with those of IL-4, especially with regard to changes induced on hematopoietic cells, but these effects are probably less important given the more potent role of IL-4. IL-13 induces matrix metalloproteinases (MMPs) as part of a mechanism that protects against excessive allergic inflammation that predisposes to asphyxiation. IL-13 induces many features of allergic lung disease, including airway hyperresponsiveness, goblet cell metaplasia and mucus hypersecretion, which all contribute to airway obstruction.
- Molecular Weight
- 38.8 kDa
- Pathways
- JAK-STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
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