CCL3 Protein (AA 24-92)
Quick Overview for CCL3 Protein (AA 24-92) (ABIN6952188)
Target
See all CCL3 ProteinsProtein Type
Biological Activity
Origin
Source
Application
Purity
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Protein Characteristics
- AA 24-92
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Sequence
- SLAADTPTAC CFSYTSRQIP QNFIADYFET SSQCSKPGVI FLTKRSRQVC ADPSEEWVQK YVSDLELSA
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Characteristics
- Recombinant Human CCL3 (MIP-1alpha)
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Endotoxin Level
- <0.01 EU per 1μg of the protein by the LAL method
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Biological Activity Comment
- EC50 = 0.2 nM determined by Migration Assay in cells expressing recombinant CCR5
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Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 1-92) protein (GST tag)
CCL3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 24-92) protein (His tag)CCL3 Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 23-92) protein (His tag)CCL3 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Chemokine (C-C Motif) Ligand 3 (CCL3) proteinCCL3 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 27-92) protein (Fc Tag)CCL3 Origin: Human Host: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 24-92) protein (His tag)CCL3 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Chemokine (C-C Motif) Ligand 3 (CCL3) protein (His tag)CCL3 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 24-92) protein (His tag)CCL3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90% by SDS-PAGE SDS
Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 24-92) (Active) protein (Biotin)CCL3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 97 % by SDS PAGE CMA Active
Chemokine (C-C Motif) Ligand 3 (CCL3) proteinCCL3 Origin: Rat Host: Escherichia coli (E. coli) Recombinant 95,00% SDS
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
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Storage
- -20 °C,-80 °C
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Storage Comment
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12 months from date of receipt, -20 to -70 °C as supplied.
Suggest to use immediately after reconstitution
1 month at -20 to -70 °C under sterile conditions after reconstitution. -
Expiry Date
- 12 months
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- CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))
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Alternative Name
- CCL3 (MIP-1alpha)
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Background
- Macrophage inflammatory proteins 1-alpha (MIP1alpha)(CCL3) binds to cell surface receptors CCR1 and CCR5. It is proinflammatory, leading to chemotaxis and activation of immune cells. It also inhibits proliferation of hematopoietic stem cells. Moreover, by binding to one of the HIV coreceptors, CCR5, it suppresses HIV infection.
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Molecular Weight
- 7.716 kDa
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UniProt
- P10147
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Autophagy
Target
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