CCL5 Protein (AA 24-91) (Biotin)
Quick Overview for CCL5 Protein (AA 24-91) (Biotin) (ABIN6952202)
Target
See all CCL5 ProteinsProtein Type
Biological Activity
Origin
Source
Application
Purity
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Protein Characteristics
- AA 24-91
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Purification tag / Conjugate
- This CCL5 protein is labelled with Biotin.
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Sequence
- SPYSSDTTPC CFAYIARPLP RAHIKEYFYT SGKCSNPAVV FVTRKNRQVC ANPEKKWVRE YINSLEMS
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Characteristics
- Biotininylated Recombinant Human CCL5 (Rantes)
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Endotoxin Level
- <0.01 EU per 1μg of the protein by the LAL method
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Biological Activity Comment
- EC50 = 0.25-0.50 nM determined by Migration Assay of recombinant CCR5 containing cells
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Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 24-91) protein (Fc Tag)
CCL5 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 24-91) protein (His tag,SUMO Tag)CCL5 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 24-91) protein (His-Avi Tag,Biotin)CCL5 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Chemokine (C-C Motif) Ligand 5 (CCL5) protein (His tag)CCL5 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 24-91) protein (Fc Tag)CCL5 Origin: Human Host: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Chemokine (C-C Motif) Ligand 5 (CCL5) proteinCCL5 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 24-91) (Active) proteinCCL5 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 97 % by SDS PAGE CMA Active
Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 1-91) protein (GST tag)CCL5 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
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Storage
- -20 °C,-80 °C
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Storage Comment
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12 months from date of receipt, -20 to -70 °C as supplied.
Suggest to use immediately after reconstitution
1 month at -20 to -70 °C under sterile conditions after reconstitution. -
Expiry Date
- 12 months
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- CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))
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Alternative Name
- CCL5 (Rantes)
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Background
- Regulated on Activation, Normal T cell Expressed and Secreted (RANTES) (CCL5) is a proinflammatory chemokine that induces migration and activation of leukocytes, as well as implication in HIV infection. It binds to cell surface receptors CCR1, CCR3, CCR4, and CCR5. Its biological effects on leukocyte activation and HIV infection displays dependence on concentration and on the binding of cell surface glycosaminoglycans.
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Molecular Weight
- 10.270 kDa
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UniProt
- P13501
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration
Target
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