IL-8 Protein (AA 28-99)
Quick Overview for IL-8 Protein (AA 28-99) (ABIN6952234)
Target
See all IL-8 (IL8) ProteinsProtein Type
Biological Activity
Origin
Source
Application
-
-
Protein Characteristics
- AA 28-99
-
Sequence
- SAKELRCQCI KTYSKPFHPK FIKELRVIES GPHCANTEII VKLSDGRELC LDPKENWVQR VVEKFLKRAE NS
-
Characteristics
- Recombinant Human CXCL8 (IL-8)
-
Endotoxin Level
- <0.01 EU per 1μg of the protein by the LAL method
-
Biological Activity Comment
- EC50 = 0.083 nM determined by Migration Assay in cells expressing recombinant CXCR1
-
-
Want other Options for this Protein ?
!Discover Our Predefined Custom Proteins and Custom Protein Services!Your project requires further customization? Contact us and discover our custom protein solutions
-
Interleukin 8 (IL8) (AA 28-99) protein (His tag)
IL8 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 8 (IL8) (AA 28-99) (Active) protein (His tag,AVI tag,Biotin)IL8 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 8 (IL8) (AA 26-167) protein (His-IF2DI Tag)IL8 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Interleukin 8 (IL8) (AA 1-99) protein (GST tag)IL8 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 8 (IL8) (AA 28-99) protein (Fc Tag)IL8 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
Interleukin 8 (IL8) (AA 28-99) (Active) protein (Fc Tag)IL8 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Interleukin 8 (IL8) (AA 23-101), (full length) protein (His tag)IL8 Origin: Dog Host: Yeast Recombinant > 90 % ELISA
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
-
Storage
- -20 °C,-80 °C
-
Storage Comment
-
12 months from date of receipt, -20 to -70 °C as supplied.
Suggest to use immediately after reconstitution
1 month at -20 to -70 °C under sterile conditions after reconstitution. -
Expiry Date
- 12 months
-
-
- IL-8 (IL8) (Interleukin 8 (IL8))
-
Alternative Name
- CXCL8 (IL-8)
-
Background
- Interleukin 8 (IL-8 /CXCL8) is secreted primarily by macrophages and monocytes. It is one of the key mediators for inflammatory responses. IL-8 is a strong chemotractant for neutrophils and monocytes promoting activation of these cells by binding to two cell surface receptors, CXCR1 and CXCR2. It is also a strong angiogenic agent and is considered to play a role in the pathogenesis of bronchiolitis.
-
Molecular Weight
- 8.386 kDa
-
UniProt
- P10145
-
Pathways
- TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagy
Target
-
